TY  - JOUR
AU  - Senni, Michele
AU  - McMurray, John J V
AU  - Wachter, Rolf
AU  - McIntyre, Hugh F
AU  - Reyes, Antonio
AU  - Majercak, Ivan
AU  - Andreka, Peter
AU  - Shehova-Yankova, Nina
AU  - Anand, Inder
AU  - Yilmaz, Mehmet B
AU  - Gogia, Harinder
AU  - Martinez-Selles, Manuel
AU  - Fischer, Steffen
AU  - Zilahi, Zsolt
AU  - Cosmi, Franco
AU  - Gelev, Valeri
AU  - Galve, Enrique
AU  - Gómez-Doblas, Juanjo J
AU  - Nociar, Jan
AU  - Radomska, Maria
AU  - Sokolova, Beata
AU  - Volterrani, Maurizio
AU  - Sarkar, Arnab
AU  - Reimund, Bernard
AU  - Chen, Fabian
AU  - Charney, Alan
PY  - 2016
DO  - 10.1002/ejhf.548
UR  - http://hdl.handle.net/10668/10075
T2  - European journal of heart failure
AB  - To assess the tolerability of initiating/uptitrating sacubitril/valsartan (LCZ696) from 50 to 200 mg twice daily (target dose) over 3 and 6 weeks in heart failure (HF) patients (ejection fraction ≤35%). A 5-day open-label run-in (sacubitril/valsartan...
LA  - en
KW  - ARNI
KW  - Heart failure
KW  - LCZ696
KW  - Sacubitril
KW  - Tolerability
KW  - Valsartan
KW  - Aged
KW  - Aminobutyrates
KW  - Angiotensin Receptor Antagonists
KW  - Biphenyl Compounds
KW  - Double-Blind Method
KW  - Drug Combinations
KW  - Female
KW  - Heart Failure
KW  - Humans
KW  - Hyperkalemia
KW  - Hypotension
KW  - Male
KW  - Middle Aged
KW  - Neprilysin
KW  - Renal Insufficiency
KW  - Tetrazoles
KW  - Treatment Outcome
KW  - Valsartan
TI  - Initiating sacubitril/valsartan (LCZ696) in heart failure: results of TITRATION, a double-blind, randomized comparison of two uptitration regimens.
TY  - research article
VL  - 18
ER  -