RT Journal Article T1 Frequency, risk factors, and outcomes of hospital readmissions of COVID-19 patients. A1 Ramos-Martinez, Antonio A1 Parra-Ramirez, Lina Marcela A1 Morras, Ignacio A1 Carnevali, María A1 Jimenez-Ibañez, Lorena A1 Rubio-Rivas, Manuel A1 Arnalich, Francisco A1 Beato, Jose Luis A1 Monge, Daniel A1 Asin, Uxua A1 Suarez, Carmen A1 Freire, Santiago Jesus A1 Mendez-Bailon, Manuel A1 Perales, Isabel A1 Loureiro-Amigo, Jose A1 Gomez-Belda, Ana Belen A1 Pesqueira, Paula Maria A1 Gomez-Huelgas, Ricardo A1 Mella, Carmen A1 Diez-García, Luis Felipe A1 Fernandez-Sola, Joaquim A1 Gonzalez-Ferrer, Ruth A1 Aroza, Marina A1 Anton-Santos, Juan Miguel A1 Lumbreras-Bermejo, Carlos K1 Glucocorticoids K1 Hemoglobins K1 Bacterial Infections K1 Heart Failure K1 COVID‑19 AB To determine the proportion of patients with COVID-19 who were readmitted to the hospital and the most common causes and the factors associated with readmission. Multicenter nationwide cohort study in Spain. Patients included in the study were admitted to 147 hospitals from March 1 to April 30, 2020. Readmission was defined as a new hospital admission during the 30 days after discharge. Emergency department visits after discharge were not considered readmission. During the study period 8392 patients were admitted to hospitals participating in the SEMI-COVID-19 network. 298 patients (4.2%) out of 7137 patients were readmitted after being discharged. 1541 (17.7%) died during the index admission and 35 died during hospital readmission (11.7%, p = 0.007). The median time from discharge to readmission was 7 days (IQR 3-15 days). The most frequent causes of hospital readmission were worsening of previous pneumonia (54%), bacterial infection (13%), venous thromboembolism (5%), and heart failure (5%). Age [odds ratio (OR): 1.02; 95% confident interval (95% CI): 1.01-1.03], age-adjusted Charlson comorbidity index score (OR: 1.13; 95% CI: 1.06-1.21), chronic obstructive pulmonary disease (OR: 1.84; 95% CI: 1.26-2.69), asthma (OR: 1.52; 95% CI: 1.04-2.22), hemoglobin level at admission (OR: 0.92; 95% CI: 0.86-0.99), ground-glass opacification at admission (OR: 0.86; 95% CI:0.76-0.98) and glucocorticoid treatment (OR: 1.29; 95% CI: 1.00-1.66) were independently associated with hospital readmission. The rate of readmission after hospital discharge for COVID-19 was low. Advanced age and comorbidity were associated with increased risk of readmission. PB Nature Publishing Group YR 2021 FD 2021-07-02 LK http://hdl.handle.net/10668/18150 UL http://hdl.handle.net/10668/18150 LA en NO Ramos-Martínez A, Parra-Ramírez LM, Morrás I, Carnevali M, Jiménez-Ibañez L, Rubio-Rivas M, et al. Frequency, risk factors, and outcomes of hospital readmissions of COVID-19 patients. Sci Rep. 2021 Jul 2;11(1):13733 DS RISalud RD Apr 6, 2025