TY  - JOUR
AU  - André, Thierry
AU  - Shiu, Kai-Keen
AU  - Kim, Tae Won
AU  - Jensen, Benny Vittrup
AU  - Jensen, Lars Henrik
AU  - Punt, Cornelis
AU  - Smith, Denis
AU  - Garcia-Carbonero, Rocio
AU  - Benavides, Manuel
AU  - Gibbs, Peter
AU  - de la Fouchardiere, Christelle
AU  - Rivera, Fernando
AU  - Elez, Elena
AU  - Bendell, Johanna
AU  - Le, Dung T
AU  - Yoshino, Takayuki
AU  - Van Cutsem, Eric
AU  - Yang, Ping
AU  - Farooqui, Mohammed Z H
AU  - Marinello, Patricia
AU  - Diaz, Luis A
AU  - KEYNOTE-177 Investigators
PY  - 2020
DO  - 10.1056/NEJMoa2017699
UR  - http://hdl.handle.net/10668/16716
T2  - The New England journal of medicine
AB  - Programmed death 1 (PD-1) blockade has clinical benefit in microsatellite-instability-high (MSI-H) or mismatch-repair-deficient (dMMR) tumors after previous therapy. The efficacy of PD-1 blockade as compared with chemotherapy as first-line therapy for...
LA  - en
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Antibodies, Monoclonal, Humanized
KW  - Antineoplastic Agents, Immunological
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - Biomarkers, Tumor
KW  - Brain Neoplasms
KW  - Colorectal Neoplasms
KW  - Female
KW  - Fluorouracil
KW  - Humans
KW  - Immune Checkpoint Inhibitors
KW  - Kaplan-Meier Estimate
KW  - Male
KW  - Microsatellite Instability
KW  - Middle Aged
KW  - Mutation
KW  - Neoplastic Syndromes, Hereditary
KW  - Progression-Free Survival
TI  - Pembrolizumab in Microsatellite-Instability-High Advanced Colorectal Cancer.
TY  - research article
VL  - 383
ER  -