TY  - JOUR
AU  - López-Cortés, Luis F
AU  - Castaño, Manuel A
AU  - López-Ruz, Miguel A
AU  - Rios-Villegas, María J
AU  - Hernández-Quero, José
AU  - Merino, Dolores
AU  - Jiménez-Aguilar, Patricia
AU  - Marquez-Solero, Manuel
AU  - Terrón-Pernía, Alberto
AU  - Tellez-Pérez, Francisco
AU  - Viciana, Pompeyo
AU  - Orihuela-Cañadas, Francisco
AU  - Palacios-Baena, Zaira
AU  - Vinuesa-Garcia, David
AU  - Fajardo-Pico, Jose M
AU  - Romero-Palacios, Alberto
AU  - Ojeda-Burgos, Guillermo
AU  - Pasquau-Liaño, Juan
PY  - 2016
DO  - 10.1371/journal.pone.0148924
UR  - http://hdl.handle.net/10668/2259
T2  - PloS One
AB  - BACKGROUND AND OBJECTIVESignificant controversy still exists about ritonavir-boosted protease inhibitor monotherapy (mtPI/rtv) as a simplification strategy that is used up to now to treat patients that have not experienced previous virological failure...
LA  - en
PB  - Public Library of Science
KW  - Linfocitos T CD4-Positivos
KW  - Coinfección
KW  - Darunavir
KW  - Infecciones por VIH
KW  - Análisis de intención de tratar
KW  - Lopinavir
KW  - Mutación
KW  - Inhibidores de proteasas
KW  - Ritonavir
KW  - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes::CD4-Positive T-Lymphocytes
KW  - Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Infection::Coinfection
KW  - Medical Subject Headings::Diseases::Virus Diseases::RNA Virus Infections::Retroviridae Infections::Lentivirus Infections::HIV Infections
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Aspartic Acid Proteases::Aspartic Acid Endopeptidases::HIV Protease
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Epidemiologic Study Characteristics as Topic::Clinical Trials as Topic::Controlled Clinical Trials as...
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyrimidines::Pyrimidinones::Lopinavir
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Protease Inhibitors
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Retrospective Studies
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Sulfur Compounds::Thiazoles::Ritonavir
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
KW  - Medical Subject Headings::Diseases::Virus Diseases::Viremia
TI  - Effectiveness of Ritonavir-Boosted Protease Inhibitor Monotherapy in Clinical Practice Even with Previous Virological Failures to Protease Inhibitor-Based Regimens.
TY  - research article
ER  -