TY - JOUR AU - Flook, Marisa AU - Escalera-Balsera, Alba AU - Gallego-Martinez, Alvaro AU - Espinosa-Sanchez, Juan Manuel AU - Aran, Ismael AU - Soto-Varela, Andres AU - Lopez-Escamez, Jose Antonio PY - 2021 DO - 10.3390/biomedicines9111530 UR - http://hdl.handle.net/10668/4116 T2 - Biomedicines AB - Meniere Disease (MD) is a multifactorial disorder of the inner ear characterized by vertigo attacks associated with sensorineural hearing loss and tinnitus with a significant heritability. Although MD has been associated with several genes, no... LA - en PB - MDPI KW - Meniere disease KW - Cytokines KW - WGBS KW - Hearing loss KW - DNA methylation KW - Enfermedad de Meniere KW - Citocinas KW - Secuenciación completa del genoma KW - Pérdida auditiva KW - Metilación de ADN KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Molecular Structure::Base Sequence::GC Rich Sequence::CpG Islands KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::DNA Methylation KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Acidic::Aspartic Acid::N-Methylaspartate KW - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Computational Biology KW - Medical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Ear Diseases::Labyrinth Diseases::Endolymphatic Hydrops::Meniere Disease KW - Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Nervous System Physiological Phenomena::Membrane Potentials::Synaptic Potentials::Excitatory Postsynaptic Potentials KW - Medical Subject Headings::Diseases::Otorhinolaryngologic Diseases::Ear Diseases::Hearing Disorders::Hearing Loss KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Acidic::Glutamates KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence::Regulatory Sequences, Nucleic Acid TI - DNA Methylation Signature in Mononuclear Cells and Proinflammatory Cytokines May Define Molecular Subtypes in Sporadic Meniere Disease TY - research article ER -