TY  - JOUR
AU  - Apostolova, Nadezda
AU  - Iannantuoni, Francesca
AU  - Gruevska, Aleksandra
AU  - Muntane, Jordi
AU  - Rocha, Milagros
AU  - Victor, Victor M.
PY  - 2020
DO  - 10.1016/j.redox.2020.101517
UR  - http://hdl.handle.net/10668/3682
T2  - Redox Biology
AB  - Type 2 diabetes (T2D) is a very prevalent, multisystemic, chronic metabolic disorder closely related to atherosclerosis and cardiovascular diseases. It is characterised by mitochondrial dysfunction and the presence of oxidative stress. Metformin is...
LA  - en
PB  - Elsevier
KW  - Type 2 diabetes
KW  - Metformin
KW  - Oxidative stress
KW  - Pathophysiology
KW  - Treatment
KW  - Atherosclerosis
KW  - Mitochondria
KW  - Diabetes mellitus tipo 2
KW  - Metformina
KW  - Estrés oxidativo
KW  - Fisiología
KW  - Terapéutica
KW  - Aterosclerosis
KW  - Mitocondrias
KW  - Medical Subject Headings::Anatomy::Tissues::Epithelium::Endothelium
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Mitochondria
KW  - Medical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amidines::Guanidines::Biguanides::Metformin
KW  - Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases::Arterial Occlusive Diseases::Arteriosclerosis::Atherosclerosis
KW  - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Stress, Physiological::Oxidative Stress
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics
TI  - Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions
TY  - review article
ER  -