RT Journal Article
T1 Tea consumption and incidence of type 2 diabetes in Europe: the EPIC-InterAct case-cohort study.
A1 van Woudenbergh, Geertruida J.
A1 Kuijsten, Anneleen
A1 Drogan, Dagmar
A1 Boeing, Heiner
A1 Schulze, Matthias B.
A1 van der A, Daphne L.
A1 Bueno-de-Mesquita, H. Bas
A1 Spijkerman, Annemieke M. W.
A1 Romaguera, Dora
A1 Riboli, Elio
A1 Ardanaz, Eva
A1 Barricarte, Aurelio
A1 Amiano, Pilar
A1 Beulens, Joline W. J.
A1 Sluijs, Ivonne
A1 Dahm, Christina C
A1 Overvad, Kim
A1 Chirlaque, M-Doleres
A1 Clavel, Francoise
A1 Fagher-azzi, Guy
A1 Crowe, Francesca L.
A1 Eomois, Piia-Piret
A1 Teucher, Birgit
A1 Franks, Paul W.
A1 Halkjaer, Jytte
A1 Tjonneland, Anne
A1 Khaw, Kay T.
A1 Masala, Giovanna
A1 Mattiello, Amalia
A1 Quiros, J. Ramon
A1 Rolandsson, Olov
A1 Romieu, Isabelle
A1 Sacerdote, Carlotta
A1 Sanchez-Perez, Maria-Jose
A1 Tagliabue, Giovanna
A1 Tumino, Rosario
A1 Forouhi, Nita G.
A1 Sharp, Stephen
A1 Langenberg, Claudia
A1 Wareham, Nicholas J.
K1 Té
K1 Adulto
K1 Anciano
K1 Estudios de Cohortes
K1 Diabetes Mellitus Tipo 2
K1 Conducta de Ingestión de Líquido
K1 Europa
K1 Femenino
K1 Humanos
K1 Masculino
K1 Mediana Edad
K1 Dinámicas no Lineales
K1 Cuestionarios
K1 Riesgo
K1 Adulto Joven
AB BACKGROUNDIn previous meta-analyses, tea consumption has been associated with lower incidence of type 2 diabetes. It is unclear, however, if tea is associated inversely over the entire range of intake. Therefore, we investigated the association between tea consumption and incidence of type 2 diabetes in a European population.METHODOLOGY/PRINCIPAL FINDINGSThe EPIC-InterAct case-cohort study was conducted in 26 centers in 8 European countries and consists of a total of 12,403 incident type 2 diabetes cases and a stratified subcohort of 16,835 individuals from a total cohort of 340,234 participants with 3.99 million person-years of follow-up. Country-specific Hazard Ratios (HR) for incidence of type 2 diabetes were obtained after adjustment for lifestyle and dietary factors using a Cox regression adapted for a case-cohort design. Subsequently, country-specific HR were combined using a random effects meta-analysis. Tea consumption was studied as categorical variable (0, >0-<1, 1-<4, ≥ 4 cups/day). The dose-response of the association was further explored by restricted cubic spline regression. Country specific medians of tea consumption ranged from 0 cups/day in Spain to 4 cups/day in United Kingdom. Tea consumption was associated inversely with incidence of type 2 diabetes; the HR was 0.84 [95%CI 0.71, 1.00] when participants who drank ≥ 4 cups of tea per day were compared with non-drinkers (p(linear trend) = 0.04). Incidence of type 2 diabetes already tended to be lower with tea consumption of 1-<4 cups/day (HR = 0.93 [95%CI 0.81, 1.05]). Spline regression did not suggest a non-linear association (p(non-linearity) = 0.20).CONCLUSIONS/SIGNIFICANCEA linear inverse association was observed between tea consumption and incidence of type 2 diabetes. People who drink at least 4 cups of tea per day may have a 16% lower risk of developing type 2 diabetes than non-tea drinkers.
PB Public Library of Science
PB Christian Herder, German Diabetes Center -, Leibniz Center for Diabetes Research at Heinrich Heine University Duesseldorf, Germany
YR 2012
FD 2012-05-30
LK http://hdl.handle.net/10668/769
UL http://hdl.handle.net/10668/769
LA en
NO van Woudenbergh GJ, Kuijsten A, Drogan D, van der A DL, Romaguera D, Ardanaz E, et al. Tea consumption and incidence of type 2 diabetes in Europe: the EPIC-InterAct case-cohort study. PLoS ONE 2012; 7(5):e36910
NO Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 7, 2025