TY  - JOUR
AU  - Gómez, Carmela
AU  - Garcia-Navas, Rósula
AU  - Baltanás, Fernando C
AU  - Fuentes-Mateos, Rocío
AU  - Fernández-Medarde, Alberto
AU  - Calzada, Nuria
AU  - Santos, Eugenio
PY  - 2022
DO  - 10.3390/cancers14163893
SN  - 2072-6694
UR  - http://hdl.handle.net/10668/20912
T2  - Cancers
AB  - We showed previously that the ABL-mediated phosphorylation of SOS1 promotes RAC activation and contributes to BCR-ABL leukemogenesis, suggesting the relevant role of SOS1 in the pathogenesis of CML. To try and obtain direct experimental evidence of...
LA  - en
KW  - CML
KW  - GEF
KW  - RAC
KW  - RAS
KW  - SOS-KO phenotypes
KW  - SOS1
KW  - SOS2
KW  - myeloproliferative disorders
TI  - Critical Requirement of SOS1 for Development of BCR/ABL-Driven Chronic Myelogenous Leukemia.
TY  - research article
VL  - 14
ER  -