%0 Journal Article %A Forbes, Lisa R %A Vogel, Tiphanie P %A Cooper, Megan A %A Castro-Wagner, Johana %A Schussler, Edith %A Weinacht, Katja G %A Plant, Ashley S %A Su, Helen C %A Allenspach, Eric J %A Slatter, Mary %A Abinun, Mario %A Lilic, Desa %A Cunningham-Rundles, Charlotte %A Eckstein, Olive %A Olbrich, Peter %A Guillerman, R Paul %A Patel, Niraj C %A Demirdag, Yesim Y %A Zerbe, Christa %A Freeman, Alexandra F %A Holland, Steven M %A Szabolcs, Paul %A Gennery, Andrew %A Torgerson, Troy R %A Milner, Joshua D %A Leiding, Jennifer W %T Jakinibs for the treatment of immune dysregulation in patients with gain-of-function signal transducer and activator of transcription 1 (STAT1) or STAT3 mutations. %D 2018 %U http://hdl.handle.net/10668/12815 %X Treatment of the autoimmune and immune-dysregulatory features of patients with STAT1 GOF or STAT3 GOF disease remains challenging. Jakinibs have been used to treat the severe immune-dysregulation in patients with either STAT1 GOF or STAT3 GOF mutations. %~