RT Journal Article
T1 COPD is a clear risk factor for increased use of resources and adverse outcomes in patients undergoing intervention for colorectal cancer: a nationwide study in Spain.
A1 Baré, Marisa
A1 Montón, Concepción
A1 Mora, Laura
A1 Redondo, Maximino
A1 Pont, Marina
A1 Escobar, Antonio
A1 Sarasqueta, Cristina
A1 Fernández de Larrea, Nerea
A1 Briones, Eduardo
A1 Quintana, Jose Maria
K1 COPD
K1 colorectal cancer
K1 complications
K1 in-hospital mortality
K1 reintervention
AB We hypothesized that patients undergoing surgery for colorectal cancer (CRC) with COPD as a comorbidity would consume more resources and have worse in-hospital outcomes than similar patients without COPD. Therefore, we compared different aspects of the care process and short-term outcomes in patients undergoing surgery for CRC, with and without COPD. This was a prospective study and it included patients from 22 hospitals located in Spain - 472 patients with COPD and 2,276 patients without COPD undergoing surgery for CRC. Clinical variables, postintervention intensive care unit (ICU) admission, use of invasive mechanical ventilation, and postintervention antibiotic treatment or blood transfusion were compared between the two groups. The reintervention rate, presence and type of complications, length of stay, and in-hospital mortality were also estimated. Hazard ratio (HR) for hospital mortality was estimated by Cox regression models. COPD was associated with higher rates of in-hospital complications, ICU admission, antibiotic treatment, reinterventions, and mortality. Moreover, after adjusting for other factors, COPD remained clearly associated with higher and earlier in-hospital mortality. To reduce in-hospital morbidity and mortality in patients undergoing surgery for CRC and with COPD as a comorbidity, several aspects of perioperative management should be optimized and attention should be given to the usual comorbidities in these patients.
YR 2017
FD 2017-04-21
LK http://hdl.handle.net/10668/11155
UL http://hdl.handle.net/10668/11155
LA en
DS RISalud
RD Apr 18, 2025