RT Journal Article
T1 Differential inflammatory response of men and women subjected to an acute resistance exercise
A1 Aragón-Vela, Jerónimo
A1 Fontana, Luis
A1 Casuso, Rafael A.
A1 Plaza-Díaz, Julio
A1 Huertas, Jesús R.
K1 IL6
K1 Serum interleukins
K1 Inflammatory response
K1 Sex differences
K1 Strength exercise
K1 Resistance training
K1 Lipid peroxidation
K1 Athletes
K1 Interleucina-6
K1 Inflamación
K1 Características sexuales
K1 Entrenamiento de fuerza
K1 Peroxidación de lípido
K1 Atletas
AB BackgroundThe purpose of this study was to investigate the inflammatory response, lipid peroxidation and muscle damage in men and women athletes subjected to an acute resistance exercise.MethodsTwenty college athletes (10 men and 10 women) performed a half-squat exercise consisting of five incremental intensities: 20%, 40%, 60%, 80% and 100% of the one-repetition maximum. Blood samples were collected at rest, 15 min and 24 h post-test. The concentration of lipid peroxidation markers and the activities of a skeletal muscle damage marker and a cardiac muscle damage marker were determined in serum. Serum α-actin was measured as a marker of sarcomere damage. Serum levels of interleukin-6, interleukin-10, and tumor necrosis factor alpha were determined to assess the inflammatory response.ResultsInterleukin-6 levels were higher at 24 h post-test than at rest and 15 min post-test in men (p < 0.05). Moreover, men showed significantly higher hydroperoxide levels in response to resistance exercise at 24 h post-test than at 15 min post-test (p < 0.05). No differences were found in muscle damage parameters regardless of sex or the time point of the test. No differences regarding the studied variables were found when comparing among different time points in women.ConclusionOur results show a larger influence of half-squat exercises on the release of IL6 and on lipid peroxidation in men than in women at equivalent workloads.
PB Elsevier B.V.
SN 2319-4170
YR 2021
FD 2021
LK http://hdl.handle.net/10668/4382
UL http://hdl.handle.net/10668/4382
LA en
NO Aragón-Vela J, Fontana L, Casuso RA, Plaza-Díaz J, R Huertas J. Differential inflammatory response of men and women subjected to an acute resistance exercise. Biomed J. 2021 Jun;44(3):338-345.
DS RISalud
RD Apr 7, 2025