RT Journal Article
T1 The effectiveness of influenza vaccination in preventing hospitalisations of elderly individuals in two influenza seasons: a multicentre case-control study, Spain, 2013/14 and 2014/15.
A1 Domínguez, Angela
A1 Soldevila, Núria
A1 Toledo, Diana
A1 Godoy, Pere
A1 Espejo, Elena
A1 Fernandez, Maria Amelia
A1 Mayoral, José María
A1 Castilla, Jesús
A1 Egurrola, Mikel
A1 Tamames, Sonia
A1 Astray, Jenaro
A1 Morales-Suárez-Varela, María
A1 The Working Group Of The Project Pi/, 
K1 effectiveness
K1 elderly
K1 hospitalised cases, hospitalised controls
K1 influenza
K1 matched case–control
K1 vaccination
AB Influenza vaccination may limit the impact of influenza in the community. The aim of this study was to assess the effectiveness of influenza vaccination in preventing hospitalisation in individuals aged ≥ 65 years in Spain. A multicentre case-control study was conducted in 20 Spanish hospitals during 2013/14 and 2014/15. Patients aged ≥ 65 years who were hospitalised with laboratory-confirmed influenza were matched with controls according to sex, age and date of hospitalisation. Adjusted vaccine effectiveness (VE) was calculated by multivariate conditional logistic regression. A total of 728 cases and 1,826 matched controls were included in the study. Overall VE was 36% (95% confidence interval (CI): 22-47). VE was 51% (95% CI: 15-71) in patients without high-risk medical conditions and 30% (95% CI: 14-44) in patients with them. VE was 39% (95% CI: 20-53) in patients aged 65-79 years and 34% (95% CI: 11-51) in patients aged ≥ 80 years, and was greater against the influenza A(H1N1)pdm09 subtype than the A(H3N2) subtype. Influenza vaccination was effective in preventing hospitalisations of elderly individuals.
YR 2017
FD 2017
LK http://hdl.handle.net/10668/11546
UL http://hdl.handle.net/10668/11546
LA en
DS RISalud
RD Apr 18, 2025