TY  - JOUR
AU  - Molina-Zayas, Maria
AU  - Garrido-Navas, Carmen
AU  - Garcia-Puche, Jose Luis
AU  - Barwell, Julian
AU  - Pedrinaci, Susana
AU  - Atienza, Margarita Martinez
AU  - Garcia-Linares, Susana
AU  - de Haro-Muñoz, Tomas
AU  - Lorente, Jose Antonio
AU  - Serrano, M Jose
AU  - Poyatos-Andujar, Antonio
PY  - 2022
DO  - 10.1007/s00438-022-01891-5
UR  - http://hdl.handle.net/10668/20230
T2  - Molecular genetics and genomics : MGG
AB  - The aim of this study was to assess the prevalence of germline variants in cancer-predisposing genes by either targeted (BRCA1/2) or multigene NGS panel in a high-risk Hereditary Breast and Ovarian Cancer (HBOC) cohort. Samples from 824 Caucasian...
LA  - en
PB  - Springer
KW  - BRCA1
KW  - BRCA2
KW  - Hereditary breast and ovarian cancer (HBOC)
KW  - Multigene panel
KW  - NGS
KW  - Breast Neoplasms
KW  - DNA-Binding Proteins
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Germ-Line Mutation
KW  - Humans
KW  - Mastectomy
KW  - Ovarian Neoplasms
KW  - Retrospective Studies
KW  - Spain
TI  - Identification of hereditary breast and ovarian cancer germline variants in Granada (Spain): NGS perspective.
TY  - research article
VL  - 297
ER  -