TY - JOUR AU - Cabot, Gabriel AU - Zamorano, Laura AU - Moyà, Bartolomé AU - Juan, Carlos AU - Navas, Alfonso AU - Blázquez, Jesús AU - Oliver, Antonio PY - 2016 DO - 10.1128/AAC.02676-15 UR - http://hdl.handle.net/10668/9702 T2 - Antimicrobial agents and chemotherapy AB - Pseudomonas aeruginosa, a major cause of nosocomial and chronic infections, is considered a paradigm of antimicrobial resistance development. However, the evolutionary trajectories of antimicrobial resistance and the impact of mutator phenotypes... LA - en KW - Anti-Bacterial Agents KW - Bacterial Proteins KW - Base Sequence KW - Carbapenems KW - Cephalosporins KW - DNA Gyrase KW - DNA Mismatch Repair KW - DNA, Bacterial KW - Drug Resistance, Multiple, Bacterial KW - Fluoroquinolones KW - Membrane Transport Proteins KW - Microbial Sensitivity Tests KW - Mutation KW - Mutation Rate KW - Penicillin-Binding Proteins KW - Porins KW - Pseudomonas aeruginosa KW - Sequence Analysis, DNA KW - beta-Lactamases TI - Evolution of Pseudomonas aeruginosa Antimicrobial Resistance and Fitness under Low and High Mutation Rates. TY - research article VL - 60 ER -