RT Journal Article T1 Experience in Spain with the first patients in home hemodialysis treated with low-flow dialysate monitors. T2 Experiencia en España con los primeros pacientes en hemodiálisis domiciliaria tratados con monitores de bajo flujo de líquido de diálisis. A1 Slon Roblero, Maria Fernanda A1 Bajo Rubio, Maria Auxiliadora A1 González-Moya, Mercedes A1 Calviño Varela, Jesús A1 Pérez Alba, Alejandro A1 Villaro Gumpert, Juan A1 Cigarrán, Secundino A1 Vidau, Pedro A1 García Marcos, Sergio A1 Abáigar Luquin, Pedro A1 Coll Piera, Elisabet A1 Gascón Mariño, Antonio A1 Espigares, Maria José A1 Molina, Mariola D A1 Molina, Pablo K1 Adecuación K1 Adequacy K1 Dializado de bajo flujo K1 Hemodiálisis domiciliaria K1 Hemodiálisis intensiva K1 Home hemodialysis K1 Intensive hemodialysis K1 Lactate K1 Lactato K1 Low flow dialysate AB Home hemodialysis (HHD) with low-flow dialysate devices has gained popularity in recent years due to its simple design, portability, and ability to provide greater freedom of movement for our patients. However, there are doubts about the adequacy that this technology offers, since it uses monitors with low-flow bath and lactate. The aim of this study was to demonstrate the clinical benefits of low-flow HHD with the NxStage System One® recently introduced in Spain. We present the results of an observational, retrospective cohort study that included the first patients who started short daily HHD with this device in 12 Spanish centers. We analyzed the evolution of 86 patients at 0, 6 and 12 months, including data related to prescription, and evolution of biochemical parameters related to dialysis dose, anemia, mineral-bone metabolism; evolution of residual renal function, medication usage, and causes of withdrawal during the followup. We were able to demonstrate that this NxStage System One® monitor, in patients with HHD, have provided an adequate dialysis dose, with optimal ultrafiltration rate, with improvement of main biochemical markers of dialysis adequacy. The usage of this technique was associated to a decrease of antihypertensive drugs, phosphate binders and erythropoietin agents, with very good results both patient and technique survival. The simplicity of the technique, together with its good clinical outcomes, should facilitate the growth and utilization of HHD, both in incident and prevalent patients. YR 2021 FD 2021-08-12 LK http://hdl.handle.net/10668/22415 UL http://hdl.handle.net/10668/22415 LA en LA es DS RISalud RD Apr 19, 2025