TY  - JOUR
AU  - García-Guerrero, Estefanía
AU  - Pérez-Simón, José Antonio
AU  - Sánchez-Abarca, Luis Ignacio
AU  - Díaz-Moreno, Irene
AU  - De la Rosa, Miguel A
AU  - Díaz-Quintana, Antonio
PY  - 2016
DO  - 10.1371/journal.pone.0154219
UR  - http://hdl.handle.net/10668/10034
T2  - PloS one
AB  - Generating the immune response requires the discrimination of peptides presented by the human leukocyte antigen complex (HLA) through the T-cell receptor (TCR). However, how a single amino acid substitution in the antigen bonded to HLA affects the...
LA  - en
KW  - Amino Acid Sequence
KW  - Antigen Presentation
KW  - Binding Sites
KW  - HLA Antigens
KW  - Humans
KW  - Molecular Dynamics Simulation
KW  - Peptides
KW  - Protein Binding
KW  - Protein Interaction Domains and Motifs
KW  - Protein Structure, Secondary
KW  - Receptors, Antigen, T-Cell
KW  - Static Electricity
KW  - Thermodynamics
TI  - The Dynamics of the Human Leukocyte Antigen Head Domain Modulates Its Recognition by the T-Cell Receptor.
TY  - research article
VL  - 11
ER  -