RT Journal Article
T1 Exercise and Childhood Cancer-A Historical Review.
A1 Morales, Javier S
A1 Valenzuela, Pedro L
A1 Velazquez-Diaz, Daniel
A1 Castillo-Garcia, Adrian
A1 Jimenez-Pavon, David
A1 Lucia, Alejandro
A1 Fiuza-Luces, Carmen
K1 Exercise is medicine
K1 Leukemia
K1 Physical activity
K1 Solid tumors
K1 Stem cell transplantation
K1 Survival
AB Childhood cancer survivors are at risk of developing important adverse effects, many of which persist for years after the end of treatment. The implementation of interventions aiming at attenuating tumor/treatment-associated adverse effects is therefore a major issue in pediatric oncology, and there is growing evidence that physical exercise could help in this regard. The present review aims to summarize the main milestones achieved in pediatric exercise oncology. For this purpose, we conducted a systematic review of relevant studies written in English in the electronic database PubMed (from inception to 14 August 2021). This review traces the field of pediatric exercise oncology throughout recent history based on three fundamental pillars: (i) exercise during childhood cancer treatment; (ii) exercise during/after hematopoietic stem cell transplantation; and (iii) exercise after childhood cancer treatment. Accumulating evidence--although still preliminary in many cases--supports the safety and potential benefits of regular exercise (with no major contraindications in general) in the childhood cancer continuum, even during the most aggressive phases of treatment. Exercise can indeed represent an effective coadjuvant therapy for attenuating cancer-related adverse effects.
PB MDPI
SN 2072-6694
YR 2021
FD 2021-12-18
LK http://hdl.handle.net/10668/20858
UL http://hdl.handle.net/10668/20858
LA en
NO Morales JS, Valenzuela PL, Velázquez-Díaz D, Castillo-García A, Jiménez-Pavón D, Lucia A, et al. Exercise and Childhood Cancer-A Historical Review. Cancers (Basel). 2021 Dec 24;14(1):82
DS RISalud
RD Apr 18, 2025