TY - JOUR AU - Sanchez-Collado, Jose AU - Lopez, Jose J AU - Jardin, Isaac AU - Berna-Erro, Alejandro AU - Camello, Pedro J AU - Cantonero, Carlos AU - Smani, Tarik AU - Salido, Gines M AU - Rosado, Juan A PY - 2022 DO - 10.1007/s00018-021-04098-w UR - http://hdl.handle.net/10668/19509 T2 - Cellular and molecular life sciences : CMLS AB - The identification of two variants of the canonical pore-forming subunit of the Ca2+ release-activated Ca2+ (CRAC) channel Orai1, Orai1α and Orai1β, in mammalian cells arises the question whether they exhibit different functional characteristics.... LA - en KW - Orai1α KW - Orai1β KW - STIM1 KW - Store-operated calcium entry KW - TRPC1 KW - Calcium KW - Cations KW - Cell Membrane KW - HeLa Cells KW - Humans KW - Mutant Proteins KW - ORAI1 Protein KW - Protein Binding KW - Stromal Interaction Molecule 1 KW - TRPC Cation Channels TI - Orai1α, but not Orai1β, co-localizes with TRPC1 and is required for its plasma membrane location and activation in HeLa cells. TY - research article VL - 79 ER -