TY  - JOUR
AU  - Thabet, Khaled
AU  - Asimakopoulos, Anastasia
AU  - Shojaei, Maryam
AU  - Romero-Gomez, Manuel
AU  - Mangia, Alessandra
AU  - Irving, William L
AU  - Berg, Thomas
AU  - Dore, Gregory J
AU  - Grønbæk, Henning
AU  - Sheridan, David
AU  - Abate, Maria Lorena
AU  - Bugianesi, Elisabetta
AU  - Weltman, Martin
AU  - Mollison, Lindsay
AU  - Cheng, Wendy
AU  - Riordan, Stephen
AU  - Fischer, Janett
AU  - Spengler, Ulrich
AU  - Nattermann, Jacob
AU  - Wahid, Ahmed
AU  - Rojas, Angela
AU  - White, Rose
AU  - Douglas, Mark W
AU  - McLeod, Duncan
AU  - Powell, Elizabeth
AU  - Liddle, Christopher
AU  - van der Poorten, David
AU  - George, Jacob
AU  - Eslam, Mohammed
AU  - International Liver Disease Genetics Consortium
PY  - 2016
DO  - 10.1038/ncomms12757
UR  - http://hdl.handle.net/10668/10446
T2  - Nature communications
AB  - Cirrhosis likely shares common pathophysiological pathways despite arising from a variety of liver diseases. A recent GWAS identified rs641738, a polymorphism in the MBOAT7 locus, as being associated with the development of alcoholic cirrhosis. Here...
LA  - en
KW  - Acyltransferases
KW  - Carcinoma, Hepatocellular
KW  - Case-Control Studies
KW  - Cohort Studies
KW  - Disease Progression
KW  - Fatty Liver
KW  - Female
KW  - Hepatitis C, Chronic
KW  - Humans
KW  - Immune System
KW  - Liver Cirrhosis
KW  - Liver Neoplasms
KW  - Macrophage Activation
KW  - Male
KW  - Membrane Proteins
KW  - Middle Aged
KW  - Oxidative Stress
KW  - Polymorphism, Single Nucleotide
TI  - MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C.
TY  - research article
VL  - 7
ER  -