TY  - JOUR
AU  - Jiménez, Juan J.
AU  - Iribarren, José L.
AU  - Brouard, Maitane
AU  - Hernández, Domingo
AU  - Palmero, Salomé
AU  - Jiménez, Alejandro
AU  - Lorente, Leonardo
AU  - Machado, Patricia
AU  - Borreguero, Juan M.
AU  - Raya, José M
AU  - Martín, Beatriz
AU  - Pérez, Rosalía
AU  - Martínez, Rafael
AU  - Mora, María L.
PY  - 2011
DO  - 10.1186/1749-8090-6-138
UR  - http://hdl.handle.net/10668/361
T2  - Journal of Cardiothoracic Surgery
AB  - Background. In cardiopulmonary bypass (CPB) patients, fibrinolysis may enhance postoperative inflammatory response. We aimed to determine whether an additional postoperative dose of antifibrinolytic tranexamic acid (TA) reduced CPB-mediated...
LA  - en
PB  - BioMed Central
KW  - Cardiac surgery
KW  - Inflammatory response
KW  - Bleeding
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Surgical Procedures, Elective
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Extracorporeal Circulation::Cardiopulmonary Bypass
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Hematologic Agents::Coagulants::Hemostatics::Antifibrinolytic Agents
KW  - Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Blood Physiological Phenomena::Blood Physiological Processes::Hemostasis::Blood Coagulation::Fibrinolysis
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Carboxylic Acids::Acids, Carbocyclic::Cyclohexanecarboxylic Acids::Tranexamic Acid
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome
KW  - Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Epidemiologic Research Design::Double-Blind Method
TI  - Safety and Effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dose-dependent, phase IV clinical trial
TY  - research article
ER  -