TY - JOUR AU - Garcia-Alfonso, Pilar AU - Muñoz, Andres AU - Jimenez-Castro, Jeronimo AU - Jimenez-Fonseca, Paula AU - Pericay, Carles AU - Longo-Muñoz, Federico AU - Reyna-Fortes, Carmen AU - Argiles-Martinez, Guillem AU - Gonzalez-Astorga, Beatriz AU - Gomez-Reina, Maria Jose AU - Ruiz-Casado, Ana AU - Rodriguez-Salas, Nuria AU - Lopez-Lopez, Rafael AU - Carmona-Bayonas, Alberto AU - Conde-Herrero, Veronica AU - Aranda, Enrique PY - 2021 DO - 10.3390/cancers13184514 UR - http://hdl.handle.net/10668/3928 T2 - Cancers AB - Trifluridine/tipiracil is currently approved for metastatic colorectal cancer (mCRC) refractory to available therapies. However, there is no consensus on factors that predict treatment outcomes in daily practice. We assessed the early clinical... LA - en PB - MDPI KW - Biomarkers KW - Chemotherapy KW - Colorectal cancer KW - Combination therapy KW - Real-life KW - Trifluridine/tipiracil KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Pyrimidines::Pyrimidine Nucleosides::Thymidine::Trifluridine KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Esterases::Phosphoric Monoester Hydrolases::Alkaline Phosphatase KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Granulocytes::Neutrophils KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies::Retrospective Studies KW - Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spain KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Tumor Burden KW - Medical Subject Headings::Diseases::Digestive System Diseases::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms KW - Medical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Hematologic Diseases::Leukocyte Disorders::Leukopenia::Agranulocytosis::Neutropenia KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Disease Progression KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Regression Analysis KW - Medical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Hematologic Diseases::Blood Platelet Disorders::Thrombocytopenia KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms KW - Medical Subject Headings::Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes, Mononuclear::Lymphocytes KW - Medical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Hematologic Diseases::Anemia TI - Early Clinical Experience with Trifluridine/Tipiracil for Refractory Metastatic Colorectal Cancer: The ROS Study TY - research article ER -