%0 Generic
%A Lopez-Guerrero, J. A.
%A Mendiola, M.
%A Perez-Fidalgo, J. A.
%A Romero, I.
%A Gomez-Raposo, C.
%A Herrero, A.
%A Alarcon, J. D.
%A Esteban-Esteban, C.
%A Marquina-Ospina, G.
%A Rubio, M. J.
%A Sanchez, L.
%A Guerra, E. M.
%A Gonzalez-Martin, A.
%T A multicenter clinical registry with associated biological samples of gynecological cancer patients: Pilot study of the Spanish Ovarian Cancer Research Group (GEICO 81-T)
%D 2020
%@ 0923-7534
%U https://hdl.handle.net/10668/25338
%X Background: Accurate clinical annotations associated with biological samples are crucial for outcome research on real-world data. This study aims to create a virtual clinical registry (VCR) of gynecological cancer patients, associated with the collection of biological samples through biobanks, to support real-world studies and translational research in Spain. Methods: GEICO VCR is an observational, prospective, multicenter study involving over 60 hospitals, integrating clinical information and biological samples into four cohorts: ovarian cancer (OC), endometrial cancer (EC), cervical cancer (CC), and rare cancers (RC). A pilot study implementing the OC module was conducted in nine centers. Inclusion criteria were: 1) women diagnosed with gynecological cancer since March 2019; 2) age ≥18 years; 3) written informed consent; and 4) access to medical records. Clinical information is collected across seven data sets: Patient data (anonymized), Diagnosis, Primary Surgery, Chemotherapy, Biobank, Recurrence, and Follow-up. Collected samples include formalin-fixed and paraffin-embedded material, fresh frozen tissues, serum and plasma, lymphocytes, and ascites, which are stored at each center’s biobank using a coding system that links the samples to clinical information.
%K Pilot Projects
%K Translational Research, Biomedical
%K Biological Specimen Banks
%K Ascites
%~