TY - JOUR AU - Canet, Luz M AU - Sanchez-Maldonado, Jose M AU - Caliz, Rafael AU - Rodriguez-Ramos, Ana AU - Lupiañez, Carmen B AU - Canhão, Helena AU - Martinez-Bueno, Manuel AU - Escudero, Alejandro AU - Segura-Catena, Juana AU - Sorensen, Signe B AU - Hetland, Merete L AU - Soto-Pino, María Jose AU - Ferrer, Miguel A AU - Garcia, Antonio AU - Glintborg, Bente AU - Filipescu, Ileana AU - Perez-Pampin, Eva AU - Gonzalez-Utrilla, Alfonso AU - Nevot, Miguel Angel López AU - Conesa-Zamora, Pablo AU - Broeder, Alfons den AU - De Vita, Salvatore AU - Jacobsen, Sven Erik Hobe AU - Collantes-Estevez, Eduardo AU - Quartuccio, Luca AU - Canzian, Federico AU - Fonseca, João E AU - Coenen, Marieke J H AU - Andersen, Vibeke AU - Sainz, Juan PY - 2018 DO - 10.1038/s41397-018-0057-x UR - http://hdl.handle.net/10668/13031 T2 - The pharmacogenomics journal AB - The aim of this case-control study was to evaluate whether 47 single-nucleotide polymorphisms (SNPs) in steroid hormone-related genes are associated with the risk of RA and anti-TNF drug response. We conducted a case-control study in 3 European... LA - en PB - Nature Publishing Group KW - Antirheumatic agents KW - Arthritis, rheumatoid KW - Case-control studies KW - Cytochrome P-450 CYP2C9 KW - Cytochrome P-450 CYP3A KW - Estrogen receptor beta KW - Female KW - Gonadal steroid hormones KW - Haplotypes KW - Humans KW - Male KW - Metabolic detoxication, phase I KW - Polymorphism, single nucleotide KW - Tumor necrosisfactor-alpha KW - Ubiquitin-protein ligases TI - Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients. TY - Research article VL - 19 ER -