RT Journal Article
T1 Mediterranean, DASH, and MIND Dietary Patterns and Cognitive Function: The 2-Year Longitudinal Changes in an Older Spanish Cohort
A1 Nishi, Stephanie K.
A1 Babio, Nancy
A1 Gomez-Martinez, Carlos
A1 Martinez-Gonzalez, Miguel angel
A1 Ros, Emilio
A1 Corella, Dolores
A1 Castaner, Olga
A1 Martinez, J. Alfredo
A1 Alonso-Gomez, Angel M.
A1 Waernberg, Julia
A1 Vioque, Jesus
A1 Romaguera, Dora
A1 Lopez-Miranda, Jose
A1 Estruch, Ramon
A1 Tinahones, Francisco J.
A1 Lapetra, Jose
A1 Serra-Majem, J. Luis
A1 Bueno-Cavanillas, Aurora
A1 Tur, Josep A.
A1 Sanchez, Vicente Martin
A1 Pinto, Xavier
A1 Delgado-Rodriguez, Miguel
A1 Matia-Martin, Pilar
A1 Vidal, Josep
A1 Vazquez, Clotilde
A1 Daimiel, Lidia
A1 Razquin, Cristina
A1 Coltell, Oscar
A1 Becerra-Tomas, Nerea
A1 Fornell, Rafael de la Torre
A1 Abete, Itziar
A1 Sorto-Sanchez, Carolina
A1 Baron-Lopez, Francisco Javier
A1 Signes-Pastor, Antonio Jose
A1 Konieczna, Jadwiga
A1 Garcia-Rios, Antonio
A1 Casas, Rosa
A1 Gomez-Perez, Ana Maria
A1 Santos-Lozano, Jose Manuel
A1 Garcia-Arellano, Ana
A1 Guillem-Saiz, Patricia
A1 Ni, Jiaqi
A1 Soria-Florido, Maria Trinidad
A1 Zulet, M. angeles
A1 Vaquero-Luna, Jessica
A1 Toledo, Estefania
A1 Fito, Montserrat
A1 Salas-Salvado, Jordi
K1 cognition
K1 dietary pattern
K1 Mediterranean diet (MedDiet)
K1 DASH diet
K1 MIND diet
K1 Physical-activity questionnaire
K1 Mental-state
K1 Decline
K1 Adherence
K1 Impairment
K1 Disease
K1 Health
K1 Adults
K1 Intervention
K1 Association
AB Background and Aims: Plant-forward dietary patterns have been associated with cardiometabolic health benefits, which, in turn, have been related to cognitive performance with inconsistent findings. The objective of this study was to examine the relationship between baseline adherence to three a priori dietary patterns (Mediterranean, DASH, and MIND diets) with 2-year changes in cognitive performance in older adults with overweight or obesity and high cardiovascular disease risk.Methods: A prospective cohort analysis was conducted within the PREDIMED-Plus trial, involving 6,647 men and women aged 55-75 years with overweight or obesity and metabolic syndrome. Using a validated, semiquantitative 143-item food frequency questionnaire completed at baseline, the dietary pattern adherence scores were calculated. An extensive neuropsychological test battery was administered at baseline and 2-year follow-up. Multivariable-adjusted linear regression models were used to assess associations between 2-year changes in cognitive function z-scores across tertiles of baseline adherence to the a priori dietary patterns.Results: Adherence to the Mediterranean diet at baseline was associated with 2-year changes in the general cognitive screening Mini-Mental State Examination (MMSE, beta: 0.070; 95% CI: 0.014, 0.175, P-trend = 0.011), and two executive function-related assessments: the Trail Making Tests Part A (TMT-A, beta: -0.054; 95% CI: -0.110, - 0.002, P-trend = 0.047) and Part B (TMT-B, beta: -0.079; 95% CI: -0.134, -0.024, P-trend = 0.004). Adherence to the MIND diet was associated with the backward recall Digit Span Test assessment of working memory (DST-B, beta: 0.058; 95% CI: 0.002, 0.114, P-trend = 0.045). However, higher adherence to the DASH dietary pattern was not associated with better cognitive function over a period of 2 years.Conclusion: In older Spanish individuals with overweight or obesity and at high cardiovascular disease risk, higher baseline adherence to the Mediterranean dietary pattern may be associated with better cognitive performance than lower adherence over a period of 2 years.
PB Frontiers media sa
SN 1663-4365
YR 2021
FD 2021-12-13
LK https://hdl.handle.net/10668/25677
UL https://hdl.handle.net/10668/25677
LA en
DS RISalud
RD Apr 4, 2025