TY - JOUR AU - Restrepo, Clara AU - Gutierrez-Rivas, Mónica AU - Pacheco, Yolanda M AU - García, Marcial AU - Blanco, Julià AU - Medrano, Luz M AU - Navarrete-Muñoz, María A AU - Gutiérrez, Félix AU - Miralles, Pilar AU - Dalmau, David AU - Gómez, Juan Luis AU - Górgolas, Miguel AU - Cabello, Alfonso AU - Resino, Salvador AU - Benito, José M AU - Rallón, Norma AU - CoRIS and the HIV Biobank integrated in the Spanish AIDS Research Network Project RIS/EPICLIN 10_2015 PY - 2019 DO - 10.1371/journal.pone.0214421 UR - http://hdl.handle.net/10668/13765 T2 - PloS one AB - We investigated the association of genetic polymorphisms in chemokine and chemokine receptor genes with poor immunological recovery in HIV patients starting combined antiretroviral therapy (cART) with low CD4 T-cell counts. A case-control study was... LA - en KW - Adult KW - Antiretroviral Therapy, Highly Active KW - CD4 Lymphocyte Count KW - Chemokine CXCL12 KW - Female KW - HIV Infections KW - Humans KW - Immune Tolerance KW - Male KW - Middle Aged KW - Polymorphism, Genetic KW - Receptors, CCR2 KW - Retrospective Studies KW - Treatment Outcome KW - Virus Replication TI - Genetic variation in CCR2 and CXCL12 genes impacts on CD4 restoration in patients initiating cART with advanced immunesupression. TY - research article VL - 14 ER -