%0 Journal Article %A Torres, Maria J %T The complexity of drug hypersensitivity reactions. %D 2021 %U http://hdl.handle.net/10668/16086 %X Drug hypersensitivity reactions (DHRs) represent a global threat to healthcare systems due to their incidence, with a significant increase over the last years. DHR figures are overestimated in the general population since <40% of cases initially labelled as allergic can be confirmed as such when evaluated in an allergy unit. Achieving an accurate diagnosis is complex and time-consuming; besides, tests must be tailored to specific clinical manifestations and underlying mechanisms and will depend on the culprit drugs. %K IgE %K T cells %K Allergy diagnosis %K Drug allergy %K Immunologic tests %~