%0 Journal Article
%A Somoza, Maria Luisa
%A Perez-Sanchez, Natalia
%A Victorio-Puche, Laura
%A Martin-Pedraza, Laura
%A Esteban Rodriguez, Angel
%A Blanca-Lopez, Natalia
%A Abel-Fernandez Gonzalez, Eva
%A Ruano-Zaragoza, Maria
%A Prieto-Moreno-Pfeifer, Ana
%A Fernandez-Caldas, Enrique
%A Moran-Morales, Miriam
%A Fernandez-Sanchez, Francisco Javier
%A Lopez-Sanchez, Jose Damian
%A Jimenez-Rodriguez, Teodorikez Wilfox
%A Subiza-Garrido-Lestache, Jose Luis
%A Canto-Diez, Gabriela
%A Blanca-Gomez, Miguel
%A Cornejo-Garcia, Jose Antonio
%T Subjects develop tolerance to Pru p 3 but respiratory allergy to Pru p 9: A large study group from a peach exposed population.
%D 2021
%U http://hdl.handle.net/10668/18393
%X Peach tree allergens are present in fruit, pollen, branches, and leaves, and can induce systemic, respiratory, cutaneous, and gastrointestinal symptoms. We studied the capacity of peach fruit/Pru p 1, Pru p 3, Pru p 4, Pru p 7 and peach pollen/Pru p 9 for inducing symptoms following oral or respiratory exposure in a large group of subjects. We included 716 adults (aged 21 to 83 y.o.) exposed to peach tree pollen and fruit intake in the study population. Participants completed a questionnaire and were skin tested with a panel of inhalant and food allergens, including peach tree pollen, Pru p 9 and peach fruit skin extract. Immunoglobulin E antibodies (SIgE) to Pru p 1, Pru p 3, Pru p 4 and Pru p 7 were quantified. Sensitised subjects underwent oral food challenge with peach fruit and nasal provocation test with peach tree pollen and Pru p 9. The prevalence of sensitisation to peach fruit was 5% and most of these had SIgE to Pru p 3, with a very low proportion to Pru p 4 SIgE and no SIgE to Pru p 1 and Pru p 7. In only 1.8%, anaphylaxis was the clinical entity induced. Cases with positive skin tests to peach and SIgE to Pru p 3 presented a good tolerance after oral challenge with peach fruit. The prevalence of skin sensitisation to peach tree pollen was 22%, with almost half recognising Pru p 9. This induced respiratory symptoms in those evaluated by nasal provocation. In a large population group exposed to peach fruit and peach tree pollen, most individuals were tolerant, even in those with SIgE to Pru p 3. A positive response to Pru p 9 was associated with respiratory allergy.
%K Population Groups
%K Prunus persica
%K Young Adult
%~