TY - JOUR AU - Abad, A AU - Martinez-Balibrea, E AU - Vieitez, J M AU - Alonso-Orduña, V AU - Garcia Alfonso, P AU - Manzano, J L AU - Massuti, B AU - Benavides, M AU - Carrato, A AU - Zanui, M AU - Gallego, J AU - Gravalos, C AU - Conde, V AU - Provencio, M AU - Valladares-Ayerbes, M AU - Salazar, R AU - Sastre, J AU - Montagut, C AU - Rivera, F AU - Aranda, E PY - 2017 DO - 10.1093/annonc/mdx737 UR - http://hdl.handle.net/10668/11804 T2 - Annals of oncology : official journal of the European Society for Medical Oncology AB - There has been little progress toward personalized therapy for patients with metastatic colorectal cancer (mCRC). TYMS-3' untranslated region (UTR) 6 bp ins/del and ERCC1-118C/T polymorphisms were previously reported to facilitate selecting patients... LA - en PB - Elsevier KW - Colorectal cancer KW - Polymorphisms KW - Biomarkers KW - Bevacizumab KW - Oxaliplatin KW - Irinotecan KW - Adult KW - Aged KW - Aged, 80 and over KW - Antineoplastic combined chemotherapy protocols KW - Biomarkers, tumor KW - Colorectal neoplasms KW - DNA-binding proteins KW - Endonucleases KW - Female KW - Genotype KW - Humans KW - Male KW - Middle aged KW - Patient selection KW - Pharmacogenomic testing KW - Pharmacogenomic variants KW - Precision medicine KW - Progression-free survival KW - Thymidylate synthase KW - Treatment outcome TI - Genotype-based selection of treatment of patients with advanced colorectal cancer (SETICC): a pharmacogenetic-based randomized phase II trial. TY - Research article VL - 29 ER -