RT Journal Article
T1 Sociodemographic factors and clinical conditions associated to hospitalization in influenza A (H1N1) 2009 virus infected patients in Spain, 2009-2010.
A1 González-Candelas, Fernando
A1 Astray, Jenaro
A1 Alonso, Jordi
A1 Castro, Ady
A1 Cantón, Rafael
A1 Galán, Juan Carlos
A1 Garin, Olatz
A1 Sáez, Marc
A1 Soldevila, Nuria
A1 Baricot, Maretva
A1 Castilla, Jesús
A1 Godoy, Pere
A1 Delgado-Rodríguez, Miguel
A1 Martín, Vicente
A1 Mayoral, José María
A1 Pumarola, Tomás
A1 Quintana, José María
A1 Tamames, Sonia
A1 Domínguez, Angela
K1 Subtipo H1N1 del Virus de la Influenza A
K1 Gripe humana
AB The emergence and pandemic spread of a new strain of influenza A (H1N1) virus in 2009 resulted in a serious alarm in clinical and public health services all over the world. One distinguishing feature of this new influenza pandemic was the different profile of hospitalized patients compared to those from traditional seasonal influenza infections. Our goal was to analyze sociodemographic and clinical factors associated to hospitalization following infection by influenza A(H1N1) virus. We report the results of a Spanish nationwide study with laboratory confirmed infection by the new pandemic virus in a case-control design based on hospitalized patients. The main risk factors for hospitalization of influenza A (H1N1) 2009 were determined to be obesity (BMI≥40, with an odds-ratio [OR] 14.27), hematological neoplasia (OR 10.71), chronic heart disease, COPD (OR 5.16) and neurological disease, among the clinical conditions, whereas low education level and some ethnic backgrounds (Gypsies and Amerinds) were the sociodemographic variables found associated to hospitalization. The presence of any clinical condition of moderate risk almost triples the risk of hospitalization (OR 2.88) and high risk conditions raise this value markedly (OR 6.43). The risk of hospitalization increased proportionally when for two (OR 2.08) or for three or more (OR 4.86) risk factors were simultaneously present in the same patient. These findings should be considered when a new influenza virus appears in the human population.
PB Public library of Science
YR 2012
FD 2012-03-07
LK http://hdl.handle.net/10668/748
UL http://hdl.handle.net/10668/748
LA en
NO González-Candelas F, Astray J, Alonso J, Castro A, Cantón R, Galán JC, et al. Sociodemographic factors and clinical conditions associated to hospitalization in influenza A (H1N1) 2009 virus infected patients in Spain, 2009-2010. PLoS ONE; 7(3):e33139
NO Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 6, 2025