RT Journal Article
T1 The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children.
A1 Navajas-Porras, Beatriz
A1 Perez-Burillo, Sergio
A1 Hinojosa-Nogueira, Daniel
A1 Douros, Konstantinos
A1 Pastoriza, Silvia
A1 Rufian-Henares, Jose Angel
K1 antioxidant capacity
K1 children
K1 gut microbiota
K1 in vitro digestion
K1 in vitro fermentation
K1 obesity
AB The prevalence of obesity has been increasing in children over the last few decades, becoming a concern for health professionals and governments. Gut microbial community structure in obese people have been found to differ from that of lean subjects for some taxa which could result in different production of microbial metabolites. The aim of the present work was to study whether the gut microbiota from obese children extracts a different concentration of antioxidant capacity than the gut microbiota from lean children. For this purpose, different foods were in vitro digested and in vitro fermented using fecal material from obese and lean children. FRAP, DPPH and Folin-Ciocalteu methods were used to measure the antioxidant capacity released during digestion and fermentation. Overall, when using lean gut microbiota, antioxidant capacity released was higher when measured via DPPH and FRAP. Moreover, according to DPPH results, lean gut microbiota could potentially release more antioxidant power from vegetables than from animal products, while obese gut microbiota did the opposite. On the contrary, with the FRAP method obese gut microbiota released higher levels of antioxidant power from plant products than from animal products, but the final antioxidant capacity was still lower than that released by lean gut microbiota. Therefore, these results reflect that the total antioxidant capacity of foods is influenced by the gut microbiota, although whether that antioxidant capacity is released from plant or animal products can be slightly influenced by the method used for analysis.
PB MDPI AG
YR 2022
FD 2022-07-05
LK http://hdl.handle.net/10668/21487
UL http://hdl.handle.net/10668/21487
LA en
NO Navajas-Porras B, Pérez-Burillo S, Hinojosa-Nogueira D, Douros K, Pastoriza S, Rufián-Henares JÁ. The Gut Microbiota of Obese Children Releases Lower Antioxidant Capacity from Food than That of Lean Children. Nutrients. 2022 Jul 9;14(14):2829
NO This work was supported by the European Research Commission (Research ExecutiveAgency) under de research project Stance4Health under Grant (Contract Nº 816303) granted to JoséÁ. Rufián Henares and by the Plan Propio de Investigación y Transferencia of the University ofGranada under the program “Intensificación de la Investigación, modalidad B”, granted to José Á.Rufián Henares
DS RISalud
RD Apr 12, 2025