TY - JOUR AU - Esquinas, Cristina AU - Serreri, Sonia AU - Barrecheguren, Miriam AU - Rodriguez, Esther AU - Nuñez, Alexa AU - Casas-Maldonado, Francisco AU - Blanco, Ignacio AU - Pirina, Pietro AU - Lara, Beatriz AU - Miravitlles, Marc PY - 2018 DO - 10.2147/COPD.S155226 UR - http://hdl.handle.net/10668/12307 T2 - International journal of chronic obstructive pulmonary disease AB - The clinical course of alpha-1 antitrypsin deficiency (AATD) is very heterogeneous. It is estimated that 60% of individuals with severe AATD (Pi*ZZ) develop emphysema. The main objective of this study was to describe the outcomes of long-term lung... LA - en KW - alpha-1 antitrypsin deficiency KW - lung function KW - registers KW - Adult KW - Aged KW - Chi-Square Distribution KW - Disease Progression KW - Female KW - Forced Expiratory Volume KW - Humans KW - Linear Models KW - Lung KW - Male KW - Middle Aged KW - Multivariate Analysis KW - Phenotype KW - Pneumonia KW - Prognosis KW - Pulmonary Emphysema KW - Registries KW - Retrospective Studies KW - Risk Factors KW - Smoking KW - Spain KW - Spirometry KW - Time Factors KW - alpha 1-Antitrypsin Deficiency TI - Long-term evolution of lung function in individuals with alpha-1 antitrypsin deficiency from the Spanish registry (REDAAT). TY - research article VL - 13 ER -