TY - JOUR AU - Ruano, Diego PY - 2021 DO - 10.3389/fmolb.2021.658742 UR - http://hdl.handle.net/10668/4244 T2 - Frontiers in Molecular Biosciences AB - Aging is a biological and multifactorial process characterized by a progressive and irreversible deterioration of the physiological functions leading to a progressive increase in morbidity. In the next decades, the world population is expected to... LA - en PB - Frontiers KW - Aging KW - Proteasome KW - Autophagy KW - Inflammation KW - Proteostasis KW - Cell stress and aging KW - Amyotrophic lateral sclerosis KW - Molecular chaperones KW - Envejecimiento KW - Inhibidores de proteasoma KW - Autofagia KW - Inflamación KW - Senescencia celular KW - Esclerosis amiotrófica lateral KW - Chaperonas moleculares KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged KW - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Proteostasis Deficiencies KW - Medical Subject Headings::Diseases::Nervous System Diseases::Neurodegenerative Diseases::Motor Neuron Disease::Amyotrophic Lateral Sclerosis KW - Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Cognition::Comprehension KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Data Collection::Vital Statistics::Morbidity::Incidence KW - Medical Subject Headings::Diseases::Neoplasms KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Aging KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Molecular Chaperones KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors KW - Medical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus TI - Proteostasis Dysfunction in Aged Mammalian Cells. The Stressful Role of Inflammation TY - review article ER -