RT Journal Article T1 Impact of Detection Mode in a Large Cohort of Women Taking Part in a Breast Screening Program. A1 García, Marilina A1 Redondo, Maximino A1 Zarcos, Irene A1 Louro, Javier A1 Rivas-Ruiz, Francisco A1 Téllez, Teresa A1 Pérez, Diego A1 Medina Cano, Francisco A1 Machan, Kenza A1 Domingo, Laia A1 Del Mar Vernet, Maria A1 Padilla-Ruiz, Maria A1 Castells, Xavier A1 Sala, Maria K1 Breast cancer K1 risk factors K1 screening K1 survival AB The aim of this study was to evaluate the existing survival rate and clinical-pathological differences among patients with breast cancer detected by mammographic screening. This multicenter cohort study examined 1,248 patients who took part in a national screening program for the early detection of breast cancer over an eight-year period. Of the two patient subgroups (interval and screening), we found significant differences in the distribution of prognostic factors, with interval cases presenting at a lower mean age (p = 0.002), with higher percentages of human epidermal growth factor receptor 2 (HER-2) or triple negative and lower percentages of luminal A or luminal B carcinomas (p = 0.001), advanced stages (p Our results highlight that breast tumors detected during the first screening round are frequently characterized by a more benign phenotype than the rest of the screening subgroups, which could be of help when stratifying the risk of death and selecting the best treatment option for each patient. SN 2587-0831 YR 2022 FD 2022-04-01 LK http://hdl.handle.net/10668/21636 UL http://hdl.handle.net/10668/21636 LA en DS RISalud RD Apr 12, 2025