RT Journal Article T1 Comprehensive management of paranasal sinus fungus balls: A Young-IFOS consensus statement. A1 Saibene, Alberto Maria A1 Allevi, Fabiana A1 Calvo-Henriquez, Christian A1 Dauby, Nicolas A1 Dondossola, Daniele A1 Hervochon, Rémi A1 Lechien, Jérome R A1 Lobo-Duro, David A1 Locatello, Luca Giovanni A1 Maniaci, Antonino A1 Mannelli, Giuditta A1 Mayo-Yáñez, Miguel A1 Maza-Solano, Juan A1 Radulesco, Thomas A1 Tan, Neil A1 Tincati, Camilla A1 Tucciarone, Manuel A1 Vaira, Luigi Angelo A1 Sowerby, Leigh K1 antibiotics K1 computed tomography K1 endoscopy K1 guideline K1 maxillary sinus K1 mycosis AB Paranasal sinus fungus balls (PSFB) are a common form of surgically treatable, noninvasive mycosis. To date, no guidelines have standardized PSFB treatment or management of difficult cases (eg, immunocompromised or fragile patients). The clinical consensus statement presented herein aims to provide a comprehensive management guide to PSFB based on current evidence. A multidisciplinary, international panel of 19 specialists judged statements in 3 rounds of a modified Delphi method survey. Statements encompassed the following PSFB management issues: definition, diagnostic workup; treatment indications and modalities; and follow-up. Otolaryngologists, maxillofacial surgeons, infectious disease specialists, and transplant physicians were considered the target audience. Among the 23 statements, 7 reached strong consensus and 16 reached consensus. Consensus was reached on the definition, diagnosis, and treatment modalities for PSFB. Postoperative follow-up modalities and scenarios with bacterial superinfection were the most debated issues. Until further data are available, these points provide a framework for the management of PSFB. Moreover, PSFB should be considered a noninvasive mycosis that is not necessarily symptomatic or related to odontogenic conditions. Although diagnosis may be incidental, endoscopy and single imaging (computed tomography or magnetic resonance imaging, with distinctive features) are required for diagnosis, whereas contrast medium would allow for differential diagnosis. Although treatment of PSFB should be considered mandatory before sinus augmentation and is recommended for symptomatic patients, immunosuppressed patients, or patients with planned immunosuppression, watchful waiting could be considered for asymptomatic patients with chronic rhinosinusitis who are provided with appropriate advice and assessment. YR 2022 FD 2022-09-23 LK http://hdl.handle.net/10668/20063 UL http://hdl.handle.net/10668/20063 LA en DS RISalud RD Apr 10, 2025