RT Journal Article
T1 Health-Related Quality of Life in Levothyroxine-Treated Hypothyroid Women and Women without Hypothyroidism: A Case-Control Study
A1 Romero-Gómez, Benjamín
A1 Guerrero-Alonso, Paula
A1 Carmona-Torres, Juan Manuel
A1 Pozuelo-Carrascosa, Diana P.
A1 Laredo-Aguilera, José Alberto
A1 Cobo-Cuenca, Ana Isabel
K1 Hypothyroidism
K1 Quality of life
K1 Health
K1 Women
K1 Thyroid hormone
K1 Hipotiroidismo
K1 Calidad de Vida
K1 Salud
K1 Mujeres
K1 Hormonas tiroideas
AB The use of levothyroxine is not always related to the elimination of the symptoms of hypothyroidism. The aim of this study is to compare the health-related quality of life (HRQOL) of a group of hypothyroid women under levothyroxine treatment with that of a group of non-hypothyroid women. Methodology: A case–control study was performed. We used convenience sampling. The case group consisted of 152 levothyroxine-treated hypothyroid women; the control group consisted of 238 women without hypothyroidism disorders. All of the participants were euthyroid according to the clinical practice guidelines. We used as instruments the Short Form-12 questionnaire (SF-12v1) and a sociodemographic questionnaire. Results: Hypothyroid women scored significantly lower in HRQOL in SF-12v1 mental and physical components than the control group (mental component summary: 41.23 ± 12.12 vs. 46.45 ± 10.22, p < 0.001; physical component summary: 49.64 ± 10.16 vs. 54.75 ± 5.76, p < 0.001). body mass index (BMI) and age showed an influence on the physical component (p < 0.001 in both variables). Adjusted for age and BMI, hypothyroidism was still related to worse scores (p < 0.001). Conclusion: Despite being euthyroid, women with hypothyroidism showed a poorer quality of life than women without hypothyroidism. Health professionals need to assess the HRQOL of women with hypothyroidism. Further research on HRQOL and hypothyroidism is needed.
PB MDPI
YR 2020
FD 2020-11-27
LK http://hdl.handle.net/10668/3971
UL http://hdl.handle.net/10668/3971
LA en
NO Romero-Gómez B, Guerrero-Alonso P, Carmona-Torres JM, Pozuelo-Carrascosa DP, Laredo-Aguilera JA, Cobo-Cuenca AI. Health-Related Quality of Life in Levothyroxine-Treated Hypothyroid Women and Women without Hypothyroidism: A Case-Control Study. J Clin Med. 2020 Nov 27;9(12):3864
DS RISalud
RD Apr 19, 2025