%0 Journal Article
%A Romero-Gómez, Benjamín
%A Guerrero-Alonso, Paula
%A Carmona-Torres, Juan Manuel
%A Pozuelo-Carrascosa, Diana P.
%A Laredo-Aguilera, José Alberto
%A Cobo-Cuenca, Ana Isabel
%T Health-Related Quality of Life in Levothyroxine-Treated Hypothyroid Women and Women without Hypothyroidism: A Case-Control Study
%D 2020
%U http://hdl.handle.net/10668/3971
%X The use of levothyroxine is not always related to the elimination of the symptoms of hypothyroidism. The aim of this study is to compare the health-related quality of life (HRQOL) of a group of hypothyroid women under levothyroxine treatment with that of a group of non-hypothyroid women. Methodology: A case–control study was performed. We used convenience sampling. The case group consisted of 152 levothyroxine-treated hypothyroid women; the control group consisted of 238 women without hypothyroidism disorders. All of the participants were euthyroid according to the clinical practice guidelines. We used as instruments the Short Form-12 questionnaire (SF-12v1) and a sociodemographic questionnaire. Results: Hypothyroid women scored significantly lower in HRQOL in SF-12v1 mental and physical components than the control group (mental component summary: 41.23 ± 12.12 vs. 46.45 ± 10.22, p < 0.001; physical component summary: 49.64 ± 10.16 vs. 54.75 ± 5.76, p < 0.001). body mass index (BMI) and age showed an influence on the physical component (p < 0.001 in both variables). Adjusted for age and BMI, hypothyroidism was still related to worse scores (p < 0.001). Conclusion: Despite being euthyroid, women with hypothyroidism showed a poorer quality of life than women without hypothyroidism. Health professionals need to assess the HRQOL of women with hypothyroidism. Further research on HRQOL and hypothyroidism is needed.
%K Hypothyroidism
%K Quality of life
%K Health
%K Women
%K Thyroid hormone
%K Hipotiroidismo
%K Calidad de Vida
%K Salud
%K Mujeres
%K Hormonas tiroideas
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