TY  - JOUR
AU  - de-Bono, Johann
AU  - Mateo, Joaquin
AU  - Fizazi, Karim
AU  - Saad, Fred
AU  - Shore, Neal
AU  - Sandhu, Shahneen
AU  - Chi, Kim N
AU  - Sartor, Oliver
AU  - Agarwal, Neeraj
AU  - Olmos, David
AU  - Thiery-Vuillemin, Antoine
AU  - Twardowski, Przemyslaw
AU  - Mehra, Niven
AU  - Goessl, Carsten
AU  - Kang, Jinyu
AU  - Burgents, Joseph
AU  - Wu, Wenting
AU  - Kohlmann, Alexander
AU  - Adelman, Carrie A
AU  - Hussain, Maha
PY  - 2020
DO  - 10.1056/NEJMoa1911440
UR  - http://hdl.handle.net/10668/15450
T2  - The New England journal of medicine
AB  - Multiple loss-of-function alterations in genes that are involved in DNA repair, including homologous recombination repair, are associated with response to poly(adenosine diphosphate-ribose) polymerase (PARP) inhibition in patients with prostate and...
LA  - en
PB  - Massachusetts Medical Society
KW  - Phthalazines
KW  - Piperazines
KW  - Poly(ADP-ribose) Polymerase Inhibitors
KW  - Progression-Free Survival
KW  - Prostatic Neoplasms, Castration-Resistant
KW  - Aged
KW  - Aged, 80 and over
KW  - Androstenes
KW  - Antineoplastic Agents
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Benzamides
KW  - Genes, BRCA1
KW  - Genes, BRCA2
KW  - Humans
KW  - Loss of Function Mutation
KW  - Male
KW  - Middle Aged
KW  - Neoplasm Metastasis
KW  - Nitriles
KW  - Phenylthiohydantoin
TI  - Olaparib for Metastatic Castration-Resistant Prostate Cancer.
TY  - research article
VL  - 382
ER  -