TY - CONF AU - Beaumont, Javier AU - Arias, Teresa AU - López, Begoña AU - Zalba, Guillermo AU - Belloqui, Oscar AU - García-Bolao, Ignacio AU - Barba, Joaquín AU - Teresa, Eduardo de AU - Díez, Javier PY - 2009 SN - 0009-7322 UR - http://hdl.handle.net/10668/1107 T2 - Circulation AB - In human heart failure (HF) peroxisome proliferator-activated receptor alpha (PPAR alpha) is downregulated and consequently, the expression of genes involved in fatty acid oxidation repressed. The L162V (rs1800206) is a functional polymorphism of the... LA - en PB - American Heart Association KW - Acil-CoA Deshidrogenasa KW - Cartilla de ADN KW - Insuficiencia Cardíaca KW - PPAR alfa KW - Humanos KW - Plásmidos KW - Polimorfismo Genético KW - ARN Mensajero KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Oxidoreductases::Oxidoreductases Acting on CH-CH Group Donors::Acyl-CoA Dehydrogenases KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleotides::Polynucleotides::Oligonucleotides::Oligodeoxyribonucleotides::DNA Primers KW - Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Heart Failure KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Receptors, Cytoplasmic and Nuclear::Peroxisome Proliferator-Activated Receptors::PPAR alpha KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Plasmids KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged TI - The L162V polymorphism of the PPARA gene is associated with stage C of heart failure. TY - conference presentation ER -