RT Conference Proceedings T1 The L162V polymorphism of the PPARA gene is associated with stage C of heart failure. A1 Beaumont, Javier A1 Arias, Teresa A1 López, Begoña A1 Zalba, Guillermo A1 Belloqui, Oscar A1 García-Bolao, Ignacio A1 Barba, Joaquín A1 Teresa, Eduardo de A1 Díez, Javier K1 Acil-CoA Deshidrogenasa K1 Cartilla de ADN K1 Insuficiencia Cardíaca K1 PPAR alfa K1 Humanos K1 Plásmidos K1 Polimorfismo Genético K1 ARN Mensajero AB In human heart failure (HF) peroxisome proliferator-activated receptor alpha (PPAR alpha) is downregulated and consequently, the expression of genes involved in fatty acid oxidation repressed. The L162V (rs1800206) is a functional polymorphism of the human PPAR alpha gene (PPARA). In the present study we have investigated whether this polymorphism is associated with the development of stage C of HF. PB American Heart Association SN 0009-7322 YR 2009 FD 2009 LK http://hdl.handle.net/10668/1107 UL http://hdl.handle.net/10668/1107 LA en NO Beaumont, Javier; Arias, Teresa; Lopez, Begona; Zalba, Guillermo; Beloqui, Oscar; Garcia-Bolao, Ignacio; et al. The L162V polymorphism of the PPARA gene is associated with stage C of heart failure. Circulation. 2009;120(18 Suppl 2):S571 NO Abstract 1921. Contents: Volume 120, Issue 18 Supplement; November 3, 2009 / Abstracts From Scientific Sessions 2009 DS RISalud RD Apr 5, 2025