%0 Generic
%A Beaumont, Javier
%A Arias, Teresa
%A López, Begoña
%A Zalba, Guillermo
%A Belloqui, Oscar
%A García-Bolao, Ignacio
%A Barba, Joaquín
%A Teresa, Eduardo de
%A Díez, Javier
%T The L162V polymorphism of the PPARA gene is associated with stage C of heart failure.
%D 2009
%@ 0009-7322
%U http://hdl.handle.net/10668/1107
%X In human heart failure (HF) peroxisome proliferator-activated receptor alpha (PPAR alpha) is downregulated and consequently, the expression of genes involved in fatty acid oxidation repressed. The L162V (rs1800206) is a functional polymorphism of the human PPAR alpha gene (PPARA). In the present study we have investigated whether this polymorphism is associated with the development of stage C of HF.
%K Acil-CoA Deshidrogenasa
%K Cartilla de ADN
%K Insuficiencia Cardíaca
%K PPAR alfa
%K Humanos
%K Plásmidos
%K Polimorfismo Genético
%K ARN Mensajero
%~