TY - JOUR AU - Julia, Antonio AU - Blanco, Francisco AU - Fernandez-Gutierrez, Benjamin AU - Gonzalez, Antonio AU - Cañete, Juan D AU - Maymo, Joan AU - Alperi-Lopez, Mercedes AU - Olive, Alex AU - Corominas, Hector AU - Martinez-Taboada, Victor AU - Gonzalez-Alvaro, Isidoro AU - Fernandez-Nebro, Antonio AU - Erra, Alba AU - Sanchez-Fernandez, Simon AU - Alonso, Arnald AU - Lopez-Lasanta, Maria AU - Tortosa, Raul AU - Codo, Laia AU - Lluis-Gelpi, Josep AU - Garcia-Montero, Andres C AU - Bertranpetit, Jaume AU - Absher, Devin AU - Myers, Richard M AU - Tornero, Jesus AU - Marsal, Sara PY - 2016 DO - 10.1002/art.39591 UR - http://hdl.handle.net/10668/9780 T2 - Arthritis & rheumatology (Hoboken, N.J.) AB - Rheumatoid factor (RF) is a well-established diagnostic and prognostic biomarker in rheumatoid arthritis (RA). However, ∼20% of RA patients are negative for this anti-IgG antibody. To date, only variation at the HLA-DRB1 gene has been associated with... LA - en PB - Wiley KW - Arthritis, Rheumatoid KW - Genetic Loci KW - Genetic Variation KW - Genome-Wide Association Study KW - Genotype KW - Homeodomain Proteins KW - Humans KW - Polymorphism, Single Nucleotide KW - Rheumatoid Factor KW - Risk KW - Transcription Factors TI - Identification of IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis in a Genome-Wide Association Study. TY - research article VL - 68 ER -