TY  - JOUR
AU  - Alcaide, Julia
AU  - Delgado, Mayte
AU  - Legerén, Marta
AU  - Jurado, José Miguel
AU  - Blancas, Isabel
AU  - Pereda, Teresa
AU  - López, Jorge
AU  - Garrido, Margarita
AU  - Sánchez, María J
AU  - García, José L
AU  - Rueda, Antonio
PY  - 2016
DO  - 10.3892/ol.2016.5068
SN  - 1792-1074
UR  - http://hdl.handle.net/10668/2623
T2  - Oncology Letters
AB  - Aflibercept is a recombinant fusion protein that acts by inhibiting tumoural angiogenesis. Efficacy data obtained in the VELOUR randomised study has contributed to the approval of aflibercept as a second-line metastatic colorectal cancer (mCRC)...
LA  - en
PB  - Spandidos Publications
KW  - Metastatic colorectal cancer
KW  - Aflibercept
KW  - Angiogenesis
KW  - Targeted therapy
KW  - VEGF
KW  - VEGFR
KW  - Camptotecina
KW  - Neoplasias colorrectales
KW  - Ensayos de Uso compasivo
KW  - Supervivencia sin enfermedad
KW  - Humanos
KW  - Hipertensión
KW  - Mutación
KW  - Compuestos organoplatinos
KW  - Poliésteres
KW  - Proteinuria
KW  - Proteínas recombinantes de fusión
KW  - Receptores de Factores de crecimiento endotelial vascular
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Alkaloids::Camptothecin
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Therapies, Investigational::Compassionate Use Trials
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Disease-Free Survival
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Diseases::Cardiovascular Diseases::Vascular Diseases::Hypertension
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation
KW  - Medical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Hematologic Diseases::Leukocyte Disorders::Leukopenia::Agranulocytosis::Neutropenia
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Organometallic Compounds::Organoplatinum Compounds
KW  - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Polymers::Polyesters
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Urological Manifestations::Proteinuria
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Recombinant Proteins::Recombinant Fusion Proteins
KW  - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::Phosphotransferases::Phosphotransferases (Alcohol Group Acceptor)::Protein Kinases::Protein-Tyrosine Kinases::Receptor Protein-Tyrosine Kinases::Receptors,...
TI  - Efficacy and safety of aflibercept in metastatic colorectal cancer pretreated with bevacizumab: A report of five cases.
TY  - research article
ER  -