TY - JOUR AU - Moreno-Dominguez, Alejandro AU - Ortega-Saenz, Patricia AU - Gao, Lin AU - Colinas, Olalla AU - Garcia-Flores, Paula AU - Bonilla-Henao, Victoria AU - Aragones, Julian AU - Hüttemann, Maik AU - Grossman, Lawrence I AU - Weissmann, Norbert AU - Sommer, Natascha AU - Lopez-Barneo, Jose PY - 2020 DO - 10.1126/scisignal.aay9452 UR - http://hdl.handle.net/10668/14839 T2 - Science signaling AB - Acute cardiorespiratory responses to O2 deficiency are essential for physiological homeostasis. The prototypical acute O2-sensing organ is the carotid body, which contains glomus cells expressing K+ channels whose inhibition by hypoxia leads to... LA - en PB - American Association for the Advancement of Science (AAAS) KW - Arteries KW - Carotid Body KW - Hypoxia KW - Mice, Knockout KW - Mitochondria KW - Reactive Oxygen Species KW - Signal Transduction KW - Animals KW - Basic Helix-Loop-Helix Transcription Factors KW - Chemoreceptor Cells KW - Electron Transport Complex IV KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Oxygen KW - Respiratory System TI - Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors. TY - research article VL - 13 ER -