RT Journal Article T1 Association Between Soft Drink Consumption and Mortality in 10 European Countries. A1 Mullee, Amy A1 Romaguera, Dora A1 Pearson-Stuttard, Jonathan A1 Viallon, Vivian A1 Stepien, Magdalena A1 Freisling, Heinz A1 Fagherazzi, Guy A1 Mancini, Francesca Romana A1 Boutron-Ruault, Marie-Christine A1 Kühn, Tilman A1 Kaaks, Rudolf A1 Boeing, Heiner A1 Aleksandrova, Krasimira A1 Tjønneland, Anne A1 Halkjær, Jytte A1 Overvad, Kim A1 Weiderpass, Elisabete A1 Skeie, Guri A1 Parr, Christine L A1 Quirós, J Ramón A1 Agudo, Antonio A1 Sanchez-Perez, Maria-Jose A1 Amiano, Pilar A1 Cirera, Lluís A1 Ardanaz, Eva A1 Khaw, Kay-Tee A1 Tong, Tammy Y N A1 Schmidt, Julie A A1 Trichopoulou, Antonia A1 Martimianaki, Georgia A1 Karakatsani, Anna A1 Palli, Domenico A1 Agnoli, Claudia A1 Tumino, Rosario A1 Sacerdote, Carlotta A1 Panico, Salvatore A1 Bueno-de-Mesquita, Bas A1 Verschuren, W M Monique A1 Boer, Jolanda M A A1 Vermeulen, Roel A1 Ramne, Stina A1 Sonestedt, Emily A1 van Guelpen, Bethany A1 Holgersson, Pernilla Lif A1 Tsilidis, Konstantinos K A1 Heath, Alicia K A1 Muller, David A1 Riboli, Elio A1 Gunter, Marc J A1 Murphy, Neil AB Soft drinks are frequently consumed, but whether this consumption is associated with mortality risk is unknown and has been understudied in European populations to date. To examine the association between total, sugar-sweetened, and artificially sweetened soft drink consumption and subsequent total and cause-specific mortality. This population-based cohort study involved participants (n = 451 743 of the full cohort) in the European Prospective Investigation into Cancer and Nutrition (EPIC), an ongoing, large multinational cohort of people from 10 European countries (Denmark, France, Germany, Greece, Italy, the Netherlands, Norway, Spain, Sweden, and the United Kingdom), with participants recruited between January 1, 1992, and December 31, 2000. Excluded participants were those who reported cancer, heart disease, stroke, or diabetes at baseline; those with implausible dietary intake data; and those with missing soft drink consumption or follow-up information. Data analyses were performed from February 1, 2018, to October 1, 2018. Consumption of total, sugar-sweetened, and artificially sweetened soft drinks. Total mortality and cause-specific mortality. Hazard ratios (HRs) and 95% CIs were estimated using multivariable Cox proportional hazards regression models adjusted for other mortality risk factors. In total, 521 330 individuals were enrolled. Of this total, 451 743 (86.7%) were included in the study, with a mean (SD) age of 50.8 (9.8) years and with 321 081 women (71.1%). During a mean (range) follow-up of 16.4 (11.1 in Greece to 19.2 in France) years, 41 693 deaths occurred. Higher all-cause mortality was found among participants who consumed 2 or more glasses per day (vs consumers of This study found that consumption of total, sugar-sweetened, and artificially sweetened soft drinks was positively associated with all-cause deaths in this large European cohort; the results are supportive of public health campaigns aimed at limiting the consumption of soft drinks. YR 2019 FD 2019 LK http://hdl.handle.net/10668/14467 UL http://hdl.handle.net/10668/14467 LA en DS RISalud RD Apr 9, 2025