RT Journal Article T1 Burden of non-communicable disease studies in Europe: a systematic review of data sources and methodological choices. A1 Charalampous, Periklis A1 Gorasso, Vanessa A1 Plass, Dietrich A1 Pires, Sara M A1 von der Lippe, Elena A1 Mereke, Alibek A1 Idavain, Jane A1 Kissimova-Skarbek, Katarzyna A1 Morgado, Joana Nazaré A1 Ngwa, Che Henry A1 Noguer, Isabel A1 Padron-Monedero, Alicia A1 Santi-Cano, Maria Jose A1 Sarmiento, Rodrigo A1 Devleesschauwer, Brecht A1 Haagsma, Juanita A K1 Disability K1 Disability-adjusted life years (DALYs) K1 Non-communicable diseases (NCDs) K1 Burden of disease (BoD) K1 Mortality data K1 Morbidity data K1 Secondary analysis K1 Reporting guidelines AB Assessment of disability-adjusted life years (DALYs) resulting from non-communicable diseases (NCDs) requires specific calculation methods and input data. The aims of this study were to (i) identify existing NCD burden of disease (BoD) activities in Europe; (ii) collate information on data sources for mortality and morbidity; and (iii) provide an overview of NCD-specific methods for calculating NCD DALYs. NCD BoD studies were systematically searched in international electronic literature databases and in grey literature. We included all BoD studies that used the DALY metric to quantify the health impact of one or more NCDs in countries belonging to the European Region. A total of 163 BoD studies were retained: 96 (59%) were single-country or sub-national studies and 67 (41%) considered more than one country. Of the single-country studies, 29 (30%) consisted of secondary analyses using existing Global Burden of Disease (GBD) results. Mortality data were mainly derived (49%) from vital statistics. Morbidity data were frequently (40%) drawn from routine administrative and survey datasets, including disease registries and hospital discharge databases. The majority (60%) of national BoD studies reported mortality corrections. Multimorbidity adjustments were performed in 18% of national BoD studies. The number of national NCD BoD assessments across Europe increased over time, driven by an increase in BoD studies that consisted of secondary data analysis of GBD study findings. Ambiguity in reporting the use of NCD-specific BoD methods underlines the need for reporting guidelines of BoD studies to enhance the transparency of NCD BoD estimates across Europe. PB Oxford University Press YR 2022 FD 2022-01-07 LK http://hdl.handle.net/10668/19778 UL http://hdl.handle.net/10668/19778 LA en NO Charalampous P, Gorasso V, Plass D, Pires SM, von der Lippe E, Mereke A, et al. Burden of non-communicable disease studies in Europe: a systematic review of data sources and methodological choices. Eur J Public Health. 2022 Apr 1;32(2):289-296 DS RISalud RD Oct 3, 2025