RT Journal Article
T1 How to calculate the ASDAS based on C-reactive protein without individual questions from the BASDAI: the BASDAI-based ASDAS formula.
A1 Aranda-Valera, I Concepcion
A1 Garrido-Castro, Juan L
A1 Ladehesa-Pineda, Lourdes
A1 Vazquez-Mellado, Janitzia
A1 Zarco, Pedro
A1 Juanola, Xavier
A1 Gonzalez-Navas, Cristina
A1 Font-Ugalde, Pilar
A1 Castro-Villegas, M Carmen
K1 disease activity
K1 spondyloarthritis
AB To develop a new equation to calculate the Ankylosing Spondylitis Disease Activity Score based on CRP (ASDAS-CRP) using only the BASDAI total score and CRP. Axial SpA (axSpA) patients from the Cordoba Spondyloarthritis Registry cohort were recruited as a derivation cohort, while a retrospective sample from the Spanish Rheumatology Society National Registry of Spondyloarthropathies and Ibero American Spondyloarhtritis Registry registers was used as a validation cohort. We built a new equation based only on the BASDAI and CRP, defining a new formula: the BASDAI-based ASDAS (BASDAS). Linear regression analysis was used to determine the coefficients of the equation in the derivation cohort and it was subsequently validated in the validation cohort. A total of 52 axSpA patients in the derivation cohort and 3359 patients in the validation cohort were included. In the derivation cohort, the mean BASDAS [2.24 (s.d. 0.90)] was very similar to the ASDAS-CRP [2.23 (s.d. 0.95)], with a very strong correlation (r = 0.96, P  The BASDAS performs similarly to the ASDAS-CRP and can be calculated with only the BASDAI total score and CRP, allowing evaluation of disease activity in retrospective studies where the individual items of the BASDAI are not available.
YR 2020
FD 2020
LK http://hdl.handle.net/10668/14989
UL http://hdl.handle.net/10668/14989
LA en
DS RISalud
RD Apr 12, 2025