RT Journal Article
T1 Biomonitoring of Exposure to Metals in a Population Residing in an Industrial Area in Brazil: A Feasibility Study
A1 Campos, Elida
A1 Freire, Carmen
A1 Barbosa, Fernando
A1 Lemos, Cristina
A1 Saraceni, Valeria
A1 Koifman, Rosalina J.
A1 Pinheiro, Rafael do Nascimento
A1 da Silva, Ilce Ferreira
K1 survey
K1 human biomonitoring
K1 feasibility
K1 toxic metals
K1 steel industry
K1 Brazil
K1 1998 geres-iii
K1 Reference values
K1 Sao-paulo
K1 General-population
K1 Environmental-pollutants
K1 Metropolitan-area
K1 Cadmium exposure
K1 Adult-population
K1 Thyroid-hormones
K1 Steel-industry
AB Background: Industries are sources of environmental pollutants. However, there are few human biomonitoring (HBM) studies in the vicinity of industrial areas. Thus, we evaluate the feasibility of conducting an HBM study to assess exposure to metals in an industrial area in Rio de Janeiro, Brazil. Methodology: A cross-sectional survey was conducted near a steel factory. Adults (exposed = 775; controls = 775) were randomly selected and sex-matched. Subjects were interviewed using a questionnaire and a 24 h dietary recall. Blood samples were collected to analyze metal concentrations, blood count, biochemical parameters, and thyroid hormones. The feasibility of the survey was assessed following guidelines. The descriptive analysis was performed for the first 250 participants (pilot study). Results: Adjustments were made to the survey execution, including age-matching, fieldwork team, questionnaire, blood collection, and research awareness. The complete questionnaire was answered by >= 97% of participants; metals were measured in >= 98% and clinical parameters in >= 89%, except thyroid hormones (13-44%). The average age and family income were of 50 years and USD 575/month, respectively. The participants had equal distribution among sexes: 50% had a medium education level, and 59% were nonwhite. Conclusion: This preliminary HBM study demonstrates feasibility for the total population, with results indicating representativeness of the target population.
PB Mdpi
YR 2021
FD 2021-12-01
LK https://hdl.handle.net/10668/28043
UL https://hdl.handle.net/10668/28043
LA en
DS RISalud
RD Apr 18, 2025