TY - JOUR AU - Shaw, E AU - Miró, J M AU - Puig-Asensio, M AU - Pigrau, C AU - Barcenilla, F AU - Murillas, J AU - Garcia-Pardo, G AU - Espejo, E AU - Padilla, B AU - Garcia-Reyne, A AU - Pasquau, J AU - Rodriguez-Baño, J AU - López-Contreras, J AU - Montero, M AU - de la Calle, C AU - Pintado, V AU - Calbo, E AU - Gasch, O AU - Montejo, M AU - Salavert, M AU - Garcia-Pais, M J AU - Carratalà, J AU - Pujol, M PY - 2015 DO - 10.1136/bmjopen-2014-006723 UR - http://hdl.handle.net/10668/2133 T2 - BMJ Open AB - INTRODUCTIONDespite the availability of new antibiotics such as daptomycin, methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia continues to be associated with high clinical failure rates. Combination therapy has been proposed as an... LA - en PB - BMJ Publishing Group KW - Adulto KW - Antibacterianos KW - Antibióticos Antituberculosos KW - Bacteriemia KW - Daptomicina KW - Humanos KW - Análisis de Intención de Tratar KW - Meticilina KW - Staphylococcus aureus Resistente a Meticilina KW - Recurrencia KW - España KW - Insuficiencia del Tratamiento KW - Resultado del Tratamiento KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Anti-Infective Agents::Anti-Bacterial Agents::Antibiotics, Antitubercular KW - Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Bacterial Infections::Bacteremia KW - Medical Subject Headings::Chemicals and Drugs::Polycyclic Compounds::Macrocyclic Compounds::Peptides, Cyclic::Daptomycin KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Epidemiologic Study Characteristics as Topic::Clinical Trials as Topic::Controlled Clinical Trials as... KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Lactams::beta-Lactams::Penicillins::Methicillin KW - Medical Subject Headings::Organisms::Bacteria::Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Rods::Staphylococcaceae::Staphylococcus::Staphylococcus aureus::Methicillin-Resistant Staphylococcus... KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Recurrence KW - Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome::Treatment Failure KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcome TI - Daptomycin plus fosfomycin versus daptomycin monotherapy in treating MRSA: protocol of a multicentre, randomised, phase III trial. TY - research article ER -