TY  - RPRT
AU  - Espinosa, Marta
AU  - Roldan-Romero, Juan Maria
AU  - Duran, Ignacio
AU  - de-Alava, Enrique
AU  - Apellaniz-Ruiz, Maria
AU  - Cascon, Alberto
AU  - Garrigos, Carmen
AU  - Robledo, Mercedes
AU  - Rodriguez-Antona, Cristina
PY  - 2018
DO  - 10.1186/s12885-018-4467-6
UR  - http://hdl.handle.net/10668/12471
T2  - BMC cancer
AB  - Renal epithelioid angiomyolipomas (EAML) are rare tumors with aggressive behavior. EAML can be sporadic or develop within the tuberous sclerosis complex syndrome, where mutations of TSC1 or TSC2 genes (critical negative regulators of mTOR Complex 1)...
LA  - en
A3  - BioMed Central Ltd.
KW  - Renal epithelioid angiomyolipoma
KW  - Sirolimus
KW  - TSC2 mutation
KW  - mTOR pathway activation
KW  - Adult
KW  - Angiomyolipoma
KW  - Antibiotics, Antineoplastic
KW  - Chemotherapy, Adjuvant
KW  - Hepatectomy
KW  - Humans
KW  - Kidney Neoplasms
KW  - Liver Neoplasms
KW  - Male
KW  - Mutation
KW  - Nephrectomy
KW  - Signal Transduction
KW  - Sirolimus
KW  - Spinal Neoplasms
KW  - TOR Serine-Threonine Kinases
KW  - Treatment Outcome
KW  - Tuberous Sclerosis Complex 2 Protein
TI  - Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation.
TY  - report
VL  - 18
ER  -