TY - JOUR AU - García-Rodríguez, Francisco Javier AU - Martínez-Fernández, Carmen AU - Brena, David AU - Kukhtar, Dmytro AU - Serrat, Xènia AU - Nadal, Ernest AU - Boxem, Mike AU - Honnen, Sebastian AU - Miranda-Vizuete, Antonio AU - Villanueva, Alberto AU - Cerón, Julián PY - 2018 DO - 10.1242/dmm.033506 UR - http://hdl.handle.net/10668/12454 T2 - Disease models & mechanisms AB - Cisplatin and derivatives are commonly used as chemotherapeutic agents. Although the cytotoxic action of cisplatin on cancer cells is very efficient, clinical oncologists need to deal with two major difficulties, namely the onset of resistance to the... LA - en KW - Caenorhabditis elegans KW - Cisplatin KW - RNA-seq KW - Animals KW - Antineoplastic Agents KW - Apoptosis KW - Biological Assay KW - Caenorhabditis elegans KW - Caenorhabditis elegans Proteins KW - Cisplatin KW - Male KW - Mutation, Missense KW - Sequence Analysis, RNA KW - Spermatozoa KW - Transcription, Genetic TI - Genetic and cellular sensitivity of Caenorhabditis elegans to the chemotherapeutic agent cisplatin. TY - research article VL - 11 ER -